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The Impact of Low-Dose Insulin on Peripheral Nerve Insulin Receptor Signaling in Streptozotocin-Induced Diabetic Rats

BACKGROUND: The precise mechanisms of the neuroprotective effects of insulin in streptozotocin (STZ)-induced diabetic animals remain unknown, but altered peripheral nerve insulin receptor signaling due to insulin deficiency might be one cause. METHODOLOGY AND PRINCIPAL FINDINGS: Diabetes was induced...

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Detalles Bibliográficos
Autores principales: Sugimoto, Kazuhiro, Baba, Masayuki, Suzuki, Susumu, Yagihashi, Soroku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758356/
https://www.ncbi.nlm.nih.gov/pubmed/24023699
http://dx.doi.org/10.1371/journal.pone.0074247