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The Impact of Low-Dose Insulin on Peripheral Nerve Insulin Receptor Signaling in Streptozotocin-Induced Diabetic Rats
BACKGROUND: The precise mechanisms of the neuroprotective effects of insulin in streptozotocin (STZ)-induced diabetic animals remain unknown, but altered peripheral nerve insulin receptor signaling due to insulin deficiency might be one cause. METHODOLOGY AND PRINCIPAL FINDINGS: Diabetes was induced...
Autores principales: | Sugimoto, Kazuhiro, Baba, Masayuki, Suzuki, Susumu, Yagihashi, Soroku |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758356/ https://www.ncbi.nlm.nih.gov/pubmed/24023699 http://dx.doi.org/10.1371/journal.pone.0074247 |
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