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Numerous protein-bound solutes are cleared by the kidney with high efficiency

The kidney clears numerous solutes from the plasma; however, retention of these solutes causes uremic illness when the kidneys fail. We know remarkably little about which retained solutes are toxic and this limits our ability to improve dialysis therapies. To explore this we employed untargeted mass...

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Detalles Bibliográficos
Autores principales: Sirich, Tammy L., Aronov, Pavel A., Plummer, Natalie S., Hostetter, Thomas H., Meyer, Timothy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758437/
https://www.ncbi.nlm.nih.gov/pubmed/23636170
http://dx.doi.org/10.1038/ki.2013.154