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Pervasive Genetic Hitchhiking and Clonal Interference in 40 Evolving Yeast Populations

The dynamics of adaptation determines which mutations fix in a population, and hence how reproducible evolution will be. This is central to understanding the spectra of mutations recovered in evolution of antibiotic resistance(1), the response of pathogens to immune selection(2,3), and the dynamics...

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Detalles Bibliográficos
Autores principales: Lang, Gregory I., Rice, Daniel P., Hickman, Mark J., Sodergren, Erica, Weinstock, George M., Botstein, David, Desai, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758440/
https://www.ncbi.nlm.nih.gov/pubmed/23873039
http://dx.doi.org/10.1038/nature12344