Adeno-associated virus serotype 9 efficiently targets ischemic skeletal muscle following systemic delivery

Targeting therapeutic gene expression to skeletal muscle following intravenous administration is an attractive strategy for treating peripheral arterial disease (PAD), except that vector access to the ischemic limb could be a limiting factor. Since AAV serotype 9 transduces skeletal muscle at high e...

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Detalles Bibliográficos
Autores principales: Katwal, Arabindra B., Konkalmatt, Prasad R., Piras, Bryan A., Hazarika, Surovi, Li, Sean S., Lye, R. John, Sanders, John M., Ferrante, Elisa A., Yan, Zhen, Annex, Brian H., French, Brent A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758463/
https://www.ncbi.nlm.nih.gov/pubmed/23535898
http://dx.doi.org/10.1038/gt.2013.16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758463/
https://www.ncbi.nlm.nih.gov/pubmed/23535898
http://dx.doi.org/10.1038/gt.2013.16

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