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Dietary phosphate restriction suppresses phosphaturia but does not prevent FGF23 elevation in a mouse model of chronic kidney disease

Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone that in end-stage renal disease is markedly increased in serum; however, the mechanisms responsible for this increase are unclear. Here, we tested whether phosphate retention in chronic kidney disease (CKD) is responsible for the elevatio...

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Detalles Bibliográficos
Autores principales: Zhang, Shiqin, Gillihan, Ryan, He, Nan, Fields, Timothy, Liu, Shiguang, Green, Troy, Stubbs, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758787/
https://www.ncbi.nlm.nih.gov/pubmed/23698235
http://dx.doi.org/10.1038/ki.2013.194