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Metabolism of amyloid β peptide and pathogenesis of Alzheimer’s disease

The conversion of what has been interpreted as “normal brain aging” to Alzheimer’s disease (AD) via transition states, i.e., preclinical AD and mild cognitive impairment, appears to be a continuous process caused primarily by aging-dependent accumulation of amyloid β peptide (Aβ) in the brain. This...

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Detalles Bibliográficos
Autor principal: SAIDO, Takaomi C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758963/
https://www.ncbi.nlm.nih.gov/pubmed/23883611
http://dx.doi.org/10.2183/pjab.89.321