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Combined effects of estrogen deficiency and cadmium exposure on calcified hard tissues: Animal model relating to itai-itai disease in postmenopausal women

Using ovariectomized rats as a model of postmenopausal women, we studied the effects of estrogen (Es) deficiency and in combination with cadmium (Cd) exposure on the calcified hard tissues related to the development of itai-itai disease. Es deficiency suppressed the synthesis of carbonic anhydrase r...

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Detalles Bibliográficos
Autores principales: KAKEI, Mitsuo, SAKAE, Toshiro, YOSHIKAWA, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758964/
https://www.ncbi.nlm.nih.gov/pubmed/23883612
http://dx.doi.org/10.2183/pjab.89.340