Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2

Isocitrate dehydrogenase (IDH) genes 1 and 2 are frequently mutated in acute myeloid leukaemia (AML), low-grade glioma, cholangiocarcinoma (CC) and chondrosarcoma (CS). For AML, low-grade glioma and CC, mutant IDH status is associated with a DNA hypermethylation phenotype, implicating altered epigen...

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Detalles Bibliográficos
Autores principales: Guilhamon, Paul, Eskandarpour, Malihe, Halai, Dina, Wilson, Gareth A., Feber, Andrew, Teschendorff, Andrew E., Gomez, Valenti, Hergovich, Alexander, Tirabosco, Roberto, Fernanda Amary, M., Baumhoer, Daniel, Jundt, Gernot, Ross, Mark T., Flanagan, Adrienne M., Beck, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759038/
https://www.ncbi.nlm.nih.gov/pubmed/23863747
http://dx.doi.org/10.1038/ncomms3166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759038/
https://www.ncbi.nlm.nih.gov/pubmed/23863747
http://dx.doi.org/10.1038/ncomms3166

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