NMR spectroscopic detection of chirality and enantiopurity in referenced systems without formation of diastereomers

Enantiomeric excess of chiral compounds is a key parameter that determines their activity or therapeutic action. The current paradigm for rapid measurement of enantiomeric excess using NMR is based on the formation of diastereomeric complexes between the chiral analyte and a chiral resolving agent,...

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Detalles Bibliográficos
Autores principales: Labuta, Jan, Ishihara, Shinsuke, Šikorský, Tomáš, Futera, Zdeněk, Shundo, Atsuomi, Hanyková, Lenka, Burda, Jaroslav V., Ariga, Katsuhiko, Hill, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759048/
https://www.ncbi.nlm.nih.gov/pubmed/23864041
http://dx.doi.org/10.1038/ncomms3188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759048/
https://www.ncbi.nlm.nih.gov/pubmed/23864041
http://dx.doi.org/10.1038/ncomms3188

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