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NeuroD1 regulation of migration accompanies the differential sensitivity of neuroendocrine carcinomas to TrkB inhibition

The developmental transcription factor NeuroD1 is anomalously expressed in a subset of aggressive neuroendocrine tumors. Previously, we demonstrated that TrkB and neural cell adhesion molecule (NCAM) are downstream targets of NeuroD1 that contribute to the actions of neurogenic differentiation 1 (Ne...

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Detalles Bibliográficos
Autores principales: Osborne, J K, Larsen, J E, Gonzales, J X, Shames, D S, Sato, M, Wistuba, I I, Girard, L, Minna, J D, Cobb, M H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759124/
https://www.ncbi.nlm.nih.gov/pubmed/23958853
http://dx.doi.org/10.1038/oncsis.2013.24