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Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells

The Notch pathway is functionally important in breast cancer. Notch-1 has been reported to maintain an estrogen-independent phenotype in estrogen receptor α (ERα)+ breast cancer cells. Notch-4 expression correlates with Ki67. Notch-4 also plays a key role in breast cancer stem-like cells. Estrogen-i...

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Detalles Bibliográficos
Autores principales: Yun, J, Pannuti, A, Espinoza, I, Zhu, H, Hicks, C, Zhu, X, Caskey, M, Rizzo, P, D'Souza, G, Backus, K, Denning, M F, Coon, J, Sun, M, Bresnick, E H, Osipo, C, Wu, J, Strack, P R, Tonetti, D A, Miele, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759125/
https://www.ncbi.nlm.nih.gov/pubmed/23917222
http://dx.doi.org/10.1038/oncsis.2013.26