Gremlin-1 associates with fibrillin microfibrils in vivo and regulates mesothelioma cell survival through transcription factor slug

Malignant mesothelioma is a form of cancer that is highly resistant to conventional cancer therapy for which no major therapeutic advances have been introduced. Here, we identify gremlin-1, a known bone morphogenetic protein inhibitor crucial for embryonic development, as a potential therapeutic tar...

Descripción completa

Detalles Bibliográficos
Autores principales: Tamminen, J A, Parviainen, V, Rönty, M, Wohl, A P, Murray, L, Joenväärä, S, Varjosalo, M, Leppäranta, O, Ritvos, O, Sengle, G, Renkonen, R, Myllärniemi, M, Koli, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759128/
https://www.ncbi.nlm.nih.gov/pubmed/23978876
http://dx.doi.org/10.1038/oncsis.2013.29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759128/
https://www.ncbi.nlm.nih.gov/pubmed/23978876
http://dx.doi.org/10.1038/oncsis.2013.29

Ejemplares similares