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Gremlin-1 associates with fibrillin microfibrils in vivo and regulates mesothelioma cell survival through transcription factor slug
Malignant mesothelioma is a form of cancer that is highly resistant to conventional cancer therapy for which no major therapeutic advances have been introduced. Here, we identify gremlin-1, a known bone morphogenetic protein inhibitor crucial for embryonic development, as a potential therapeutic tar...
Autores principales: | Tamminen, J A, Parviainen, V, Rönty, M, Wohl, A P, Murray, L, Joenväärä, S, Varjosalo, M, Leppäranta, O, Ritvos, O, Sengle, G, Renkonen, R, Myllärniemi, M, Koli, K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759128/ https://www.ncbi.nlm.nih.gov/pubmed/23978876 http://dx.doi.org/10.1038/oncsis.2013.29 |
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