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A Mechanistic Model for Amorphous Protein Aggregation of Immunoglobulin-like Domains
[Image: see text] Protein aggregation is associated with many debilitating diseases including Alzheimer’s, Parkinson’s, and light-chain amyloidosis (AL). Additionally, such aggregation is a major problem in an industrial setting where antibody therapeutics often require high local concentrations of...
Autores principales: | Borgia, Madeleine B., Nickson, Adrian A., Clarke, Jane, Hounslow, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759167/ https://www.ncbi.nlm.nih.gov/pubmed/23510407 http://dx.doi.org/10.1021/ja308852b |
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