The Shape of the Lymphocyte Receptor Repertoire: Lessons from the B Cell Receptor

Both the B cell receptor (BCR) and the T cell receptor (TCR) repertoires are generated through essentially identical processes of V(D)J recombination, exonuclease trimming of germline genes, and the random addition of non-template encoded nucleotides. The naïve TCR repertoire is constrained by thymi...

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Detalles Bibliográficos
Autores principales: Jackson, Katherine J. L., Kidd, Marie J., Wang, Yan, Collins, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759170/
https://www.ncbi.nlm.nih.gov/pubmed/24032032
http://dx.doi.org/10.3389/fimmu.2013.00263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759170/
https://www.ncbi.nlm.nih.gov/pubmed/24032032
http://dx.doi.org/10.3389/fimmu.2013.00263

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