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Proanthocyanidin Attenuation of Oxidative Stress and NF-κB Protects Apolipoprotein E-Deficient Mice against Diabetic Nephropathy

Hyperlipidemia and hyperglycemia result in oxidative stress and play a major role in the development of diabetic nephropathy (DN). We explored the effects of proanthocyanidin (PA) on the induction and progression of DN in apolipoprotein E-deficient mice. Diabetes Mellitus was induced in ten-week-old...

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Detalles Bibliográficos
Autores principales: Al-Malki, Abdulrahman L., Sayed, Ahmed Amir Radwan, El Rabey, Haddad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759251/
https://www.ncbi.nlm.nih.gov/pubmed/24023581
http://dx.doi.org/10.1155/2013/769409