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Modeling human neurodevelopmental disorders in the Xenopus tadpole: from mechanisms to therapeutic targets
The Xenopus tadpole model offers many advantages for studying the molecular, cellular and network mechanisms underlying neurodevelopmental disorders. Essentially every stage of normal neural circuit development, from axon outgrowth and guidance to activity-dependent homeostasis and refinement, has b...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759326/ https://www.ncbi.nlm.nih.gov/pubmed/23929939 http://dx.doi.org/10.1242/dmm.012138 |