Conditional deletion of neurogenin-3 using Nkx2.1iCre results in a mouse model for the central control of feeding, activity and obesity

The ventral hypothalamus acts to integrate visceral and systemic information to control energy balance. The basic helix-loop-helix transcription factor neurogenin-3 (Ngn3) is required for pancreatic β-cell development and has been implicated in neuronal development in the hypothalamus. Here, we demo...

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Detalles Bibliográficos
Autores principales: Anthwal, Neal, Pelling, Michelle, Claxton, Suzanne, Mellitzer, Georg, Collin, Caitlin, Kessaris, Nicoletta, Richardson, William D., Gradwohl, Gérard, Ang, Siew-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759333/
https://www.ncbi.nlm.nih.gov/pubmed/23649822
http://dx.doi.org/10.1242/dmm.011916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759333/
https://www.ncbi.nlm.nih.gov/pubmed/23649822
http://dx.doi.org/10.1242/dmm.011916

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