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Loss of Pten promotes angiogenesis and enhanced vegfaa expression in zebrafish

Angiogenesis, the emergence of vessels from an existing vascular network, is pathologically associated with tumor progression and is of great interest for therapeutic intervention. PTEN is a frequently mutated tumor suppressor and has been linked to the progression of many types of tumors, including...

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Detalles Bibliográficos
Autores principales: Choorapoikayil, Suma, Weijts, Bart, Kers, Rianne, de Bruin, Alain, den Hertog, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759335/
https://www.ncbi.nlm.nih.gov/pubmed/23720233
http://dx.doi.org/10.1242/dmm.012377