Cargando…
Loss of Pten promotes angiogenesis and enhanced vegfaa expression in zebrafish
Angiogenesis, the emergence of vessels from an existing vascular network, is pathologically associated with tumor progression and is of great interest for therapeutic intervention. PTEN is a frequently mutated tumor suppressor and has been linked to the progression of many types of tumors, including...
Autores principales: | Choorapoikayil, Suma, Weijts, Bart, Kers, Rianne, de Bruin, Alain, den Hertog, Jeroen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759335/ https://www.ncbi.nlm.nih.gov/pubmed/23720233 http://dx.doi.org/10.1242/dmm.012377 |
Ejemplares similares
-
Haploinsufficiency of the genes encoding the tumor suppressor Pten predisposes zebrafish to hemangiosarcoma
por: Choorapoikayil, Suma, et al.
Publicado: (2012) -
Fine-Tuning of Pten Localization and Phosphatase Activity Is Essential for Zebrafish Angiogenesis
por: Stumpf, Miriam, et al.
Publicado: (2016) -
Macrophages trigger cardiomyocyte proliferation by increasing epicardial vegfaa expression during larval zebrafish heart regeneration
por: Bruton, Finnius A., et al.
Publicado: (2022) -
Differential Requirement for Pten Lipid and Protein Phosphatase Activity during Zebrafish Embryonic Development
por: Stumpf, Miriam, et al.
Publicado: (2016) -
HIF proteins connect the RB-E2F factors to angiogenesis
por: Bakker, Walbert. J., et al.
Publicado: (2013)