Deletion of integrin-linked kinase from neural crest cells in mice results in aortic aneurysms and embryonic lethality

Neural crest cells (NCCs) participate in the remodeling of the cardiac outflow tract and pharyngeal arch arteries during cardiovascular development. Integrin-linked kinase (ILK) is a serine/threonine kinase and a major regulator of integrin signaling. It links integrins to the actin cytoskeleton and...

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Detalles Bibliográficos
Autores principales: Arnold, Thomas D., Zang, Keling, Vallejo-Illarramendi, Ainara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759340/
https://www.ncbi.nlm.nih.gov/pubmed/23744273
http://dx.doi.org/10.1242/dmm.011866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759340/
https://www.ncbi.nlm.nih.gov/pubmed/23744273
http://dx.doi.org/10.1242/dmm.011866

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