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Deletion of integrin-linked kinase from neural crest cells in mice results in aortic aneurysms and embryonic lethality
Neural crest cells (NCCs) participate in the remodeling of the cardiac outflow tract and pharyngeal arch arteries during cardiovascular development. Integrin-linked kinase (ILK) is a serine/threonine kinase and a major regulator of integrin signaling. It links integrins to the actin cytoskeleton and...
Autores principales: | Arnold, Thomas D., Zang, Keling, Vallejo-Illarramendi, Ainara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759340/ https://www.ncbi.nlm.nih.gov/pubmed/23744273 http://dx.doi.org/10.1242/dmm.011866 |
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