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notch3 is essential for oligodendrocyte development and vascular integrity in zebrafish

Mutations in the human NOTCH3 gene cause CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy). CADASIL is an inherited small vessel disease characterized by diverse clinical manifestations including vasculopathy, neurodegeneration and dementia...

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Detalles Bibliográficos
Autores principales: Zaucker, Andreas, Mercurio, Sara, Sternheim, Nitzan, Talbot, William S., Marlow, Florence L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759344/
https://www.ncbi.nlm.nih.gov/pubmed/23720232
http://dx.doi.org/10.1242/dmm.012005