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notch3 is essential for oligodendrocyte development and vascular integrity in zebrafish
Mutations in the human NOTCH3 gene cause CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy). CADASIL is an inherited small vessel disease characterized by diverse clinical manifestations including vasculopathy, neurodegeneration and dementia...
Autores principales: | Zaucker, Andreas, Mercurio, Sara, Sternheim, Nitzan, Talbot, William S., Marlow, Florence L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759344/ https://www.ncbi.nlm.nih.gov/pubmed/23720232 http://dx.doi.org/10.1242/dmm.012005 |
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