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Functional validation of GWAS gene candidates for abnormal liver function during zebrafish liver development

Genome-wide association studies (GWAS) have revealed numerous associations between many phenotypes and gene candidates. Frequently, however, further elucidation of gene function has not been achieved. A recent GWAS identified 69 candidate genes associated with elevated liver enzyme concentrations, w...

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Detalles Bibliográficos
Autores principales: Liu, Leah Y., Fox, Caroline S., North, Trista E., Goessling, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759346/
https://www.ncbi.nlm.nih.gov/pubmed/23813869
http://dx.doi.org/10.1242/dmm.011726