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Metformin Inhibits Angiotensin II-Induced Differentiation of Cardiac Fibroblasts into Myofibroblasts

Differentiation of cardiac fibroblasts into myofibroblasts is a critical event in the progression of cardiac fibrosis that leads to pathological cardiac remodeling. Metformin, an antidiabetic agent, exhibits a number of cardioprotective properties. However, much less is known regarding the effect of...

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Detalles Bibliográficos
Autores principales: Bai, Jian, Zhang, Na, Hua, Ying, Wang, Bingjian, Ling, Lin, Ferro, Albert, Xu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759374/
https://www.ncbi.nlm.nih.gov/pubmed/24023727
http://dx.doi.org/10.1371/journal.pone.0072120