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Metformin Inhibits Angiotensin II-Induced Differentiation of Cardiac Fibroblasts into Myofibroblasts
Differentiation of cardiac fibroblasts into myofibroblasts is a critical event in the progression of cardiac fibrosis that leads to pathological cardiac remodeling. Metformin, an antidiabetic agent, exhibits a number of cardioprotective properties. However, much less is known regarding the effect of...
Autores principales: | Bai, Jian, Zhang, Na, Hua, Ying, Wang, Bingjian, Ling, Lin, Ferro, Albert, Xu, Biao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759374/ https://www.ncbi.nlm.nih.gov/pubmed/24023727 http://dx.doi.org/10.1371/journal.pone.0072120 |
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