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A Mouse Variable Gene Fragment Binds to DNA Independently of the BCR Context: A Possible Role for Immature B-Cell Repertoire Establishment

B-cell maturation occurs in several steps and requires constant stimulus for its continuing development. From the emergence of the pre-B-cell receptor, signal transduction stimulates and supports B-cell development. Current viewpoints indicate that both positive selection pressure for autoantigens a...

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Detalles Bibliográficos
Autores principales: Maranhão, Andrea Queiroz, Costa, Maria Beatriz Walter, Guedes, Leonardo, Moraes-Vieira, Pedro Manoel, Raiol, Tainá, Brigido, Marcelo Macedo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759382/
https://www.ncbi.nlm.nih.gov/pubmed/24023756
http://dx.doi.org/10.1371/journal.pone.0072625