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ERCC1 and ERCC2 Variants Predict Survival in Gastric Cancer Patients

PURPOSE: ERCC1 and ERCC2 play critical roles in the nucleotide excision repair pathway that effectively repairs DNA damage induced by chemotherapeutic agents. Therefore, functional single nucleotide polymorphisms (SNPs) in these genes could have an impact on clinical outcomes in cancer patients who...

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Detalles Bibliográficos
Autores principales: Li, Yangkai, Liu, Zhensheng, Liu, Hongliang, Wang, Li-E, Tan, Dongfeng, Ajani, Jaffer A., Wei, Qing-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759385/
https://www.ncbi.nlm.nih.gov/pubmed/24023723
http://dx.doi.org/10.1371/journal.pone.0071994