Identification and Characterization of the Regions Involved in the Nuclear Translocation of the Heterodimeric Leishmanial DNA Topoisomerase IB

Leishmania donovani, the causative organism for visceral leishmaniasis, contains a unique heterodimeric DNA-topoisomerase IB (LdTopIB). LdTopIB is a heterodimer made up of a large subunit and a small subunit that must interact with each other to build an active enzyme able to solve the topological t...

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Detalles Bibliográficos
Autores principales: Prada, Christopher F., Álvarez-Velilla, Raquel, Díaz-Gozález, Rosario, Pérez-Pertejo, Yolanda, Balaña-Fouce, Rafael, Reguera, Rosa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759442/
https://www.ncbi.nlm.nih.gov/pubmed/24023887
http://dx.doi.org/10.1371/journal.pone.0073565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759442/
https://www.ncbi.nlm.nih.gov/pubmed/24023887
http://dx.doi.org/10.1371/journal.pone.0073565

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