Depletion of CD4(+) CD25(+) Regulatory T Cells Promotes CCL21-Mediated Antitumor Immunity

CCL21 is known to attract dendritic cells (DCs) and T cells that may reverse tumor-mediated immune suppression. The massive infiltration of tumors by regulatory T cells (Tregs) prevents the development of a successful helper immune response. In this study, we investigated whether elimination of CD4(...

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Detalles Bibliográficos
Autores principales: Zhou, Shuang, Tao, Huihong, Zhen, Zhiwei, Chen, Haixia, Chen, Guolin, Yang, Yaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759453/
https://www.ncbi.nlm.nih.gov/pubmed/24023916
http://dx.doi.org/10.1371/journal.pone.0073952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759453/
https://www.ncbi.nlm.nih.gov/pubmed/24023916
http://dx.doi.org/10.1371/journal.pone.0073952

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