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Ablation of the Id2 Gene Results in Altered Circadian Feeding Behavior, and Sex-Specific Enhancement of Insulin Sensitivity and Elevated Glucose Uptake in Skeletal Muscle and Brown Adipose Tissue

Inhibitor of DNA binding 2 (ID2) is a helix-loop-helix transcriptional repressor rhythmically expressed in many adult tissues. Our earlier studies have demonstrated a role for ID2 in the input pathway, core clock function and output pathways of the mouse circadian system. We have also reported that...

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Detalles Bibliográficos
Autores principales: Mathew, Deepa, Zhou, Peng, Pywell, Cameron M., van der Veen, Daan R., Shao, Jinping, Xi, Yang, Bonar, Nicolle A., Hummel, Alyssa D., Chapman, Sarah, Leevy, W. Matthew, Duffield, Giles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759459/
https://www.ncbi.nlm.nih.gov/pubmed/24023810
http://dx.doi.org/10.1371/journal.pone.0073064