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MHC Class II Tetramers Made from Isolated Recombinant α and β Chains Refolded with Affinity-Tagged Peptides

Targeting CD4+ T cells through their unique antigen-specific, MHC class II-restricted T cell receptor makes MHC class II tetramers an attractive strategy to identify, validate and manipulate these cells at the single cell level. Currently, generating class II tetramers is a specialized undertaking e...

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Detalles Bibliográficos
Autores principales: Braendstrup, Peter, Justesen, Sune, Østerbye, Thomas, Nielsen, Lise Lotte Bruun, Mallone, Roberto, Vindeløv, Lars, Stryhn, Anette, Buus, Søren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759463/
https://www.ncbi.nlm.nih.gov/pubmed/24023895
http://dx.doi.org/10.1371/journal.pone.0073648