Luciferase Reporter Gene Assay on Human, Murine and Rat Histamine H(4) Receptor Orthologs: Correlations and Discrepancies between Distal and Proximal Readouts

The investigation of the (patho)physiological role of the histamine H(4) receptor (H(4)R) and its validation as a possible drug target in translational animal models are compromised by distinct species-dependent discrepancies regarding potencies and receptor subtype selectivities of the pharmacologi...

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Detalles Bibliográficos
Autores principales: Nordemann, Uwe, Wifling, David, Schnell, David, Bernhardt, Günther, Stark, Holger, Seifert, Roland, Buschauer, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759464/
https://www.ncbi.nlm.nih.gov/pubmed/24023919
http://dx.doi.org/10.1371/journal.pone.0073961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759464/
https://www.ncbi.nlm.nih.gov/pubmed/24023919
http://dx.doi.org/10.1371/journal.pone.0073961

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