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Luciferase Reporter Gene Assay on Human, Murine and Rat Histamine H(4) Receptor Orthologs: Correlations and Discrepancies between Distal and Proximal Readouts

The investigation of the (patho)physiological role of the histamine H(4) receptor (H(4)R) and its validation as a possible drug target in translational animal models are compromised by distinct species-dependent discrepancies regarding potencies and receptor subtype selectivities of the pharmacologi...

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Detalles Bibliográficos
Autores principales:	Nordemann, Uwe, Wifling, David, Schnell, David, Bernhardt, Günther, Stark, Holger, Seifert, Roland, Buschauer, Armin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759464/ https://www.ncbi.nlm.nih.gov/pubmed/24023919 http://dx.doi.org/10.1371/journal.pone.0073961

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