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A Critical Role for Proinflammatory Behavior of Smooth Muscle Cells in Hemodynamic Initiation of Intracranial Aneurysm

BACKGROUND: Intracranial aneurysm initiation is poorly understood, although hemodynamic insult is believed to play an important role in triggering the pathology. It has recently been found in a rabbit model that while macrophages are absent during hemodynamic aneurysm initiation, matrix metalloprote...

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Detalles Bibliográficos
Autores principales: Mandelbaum, Max, Kolega, John, Dolan, Jennifer M., Siddiqui, Adnan H., Meng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759467/
https://www.ncbi.nlm.nih.gov/pubmed/24023941
http://dx.doi.org/10.1371/journal.pone.0074357