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SIRT1 Expression Is Associated with Good Prognosis in Colorectal Cancer

BACKGROUND: Silent mating type information regulation 2 homolog 1 (SIRT1), an NAD+-dependent deacetylase, might act as a tumor promoter by inhibiting p53, but may also as a tumor suppressor by inhibiting several oncogenes such as β-catenin and survivin. Deleted in breast cancer 1 (DBC1) is known as...

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Detalles Bibliográficos
Autores principales: Jung, Wonkyung, Hong, Kwang Dae, Jung, Woon Yong, Lee, Eunjung, Shin, Bong Kyung, Kim, Han Kyeom, Kim, Aeree, Kim, Baek-hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and The Korean Society for Cytopathology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759632/
https://www.ncbi.nlm.nih.gov/pubmed/24009628
http://dx.doi.org/10.4132/KoreanJPathol.2013.47.4.332