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SIRT1 Expression Is Associated with Good Prognosis in Colorectal Cancer
BACKGROUND: Silent mating type information regulation 2 homolog 1 (SIRT1), an NAD+-dependent deacetylase, might act as a tumor promoter by inhibiting p53, but may also as a tumor suppressor by inhibiting several oncogenes such as β-catenin and survivin. Deleted in breast cancer 1 (DBC1) is known as...
Autores principales: | Jung, Wonkyung, Hong, Kwang Dae, Jung, Woon Yong, Lee, Eunjung, Shin, Bong Kyung, Kim, Han Kyeom, Kim, Aeree, Kim, Baek-hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Pathologists and The Korean Society for Cytopathology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759632/ https://www.ncbi.nlm.nih.gov/pubmed/24009628 http://dx.doi.org/10.4132/KoreanJPathol.2013.47.4.332 |
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