Cargando…

Anti-c-Met antibodies recognising a temperature sensitive epitope, inhibit cell growth

c-Met is a tyrosine receptor kinase which is activated by its ligand, the hepatocyte growth factor. Activation of c-Met leads to a wide spectrum of biological activities such as motility, angiogenesis, morphogenesis, cell survival and cell regeneration. c-Met is abnormally activated in many tumour t...

Descripción completa

Detalles Bibliográficos
Autores principales: Wong, Julin S., Warbrick, Emma, Vojtesek, Borek, Hill, Jeffrey, Lane, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759663/
https://www.ncbi.nlm.nih.gov/pubmed/23859937