Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

Senescence is a stable proliferation arrest, associated with an altered secretory pathway, thought to promote tumor suppression and tissue aging. While chromatin regulation and lamin B1 down-regulation have been implicated as senescence effectors, functional interactions between them are poorly unde...

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Detalles Bibliográficos
Autores principales: Shah, Parisha P., Donahue, Greg, Otte, Gabriel L., Capell, Brian C., Nelson, David M., Cao, Kajia, Aggarwala, Varun, Cruickshanks, Hazel A., Rai, Taranjit Singh, McBryan, Tony, Gregory, Brian D., Adams, Peter D., Berger, Shelley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759695/
https://www.ncbi.nlm.nih.gov/pubmed/23934658
http://dx.doi.org/10.1101/gad.223834.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759695/
https://www.ncbi.nlm.nih.gov/pubmed/23934658
http://dx.doi.org/10.1101/gad.223834.113

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