Cargando…
Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence
Senescence is a stress-responsive form of stable cell cycle exit. Senescent cells have a distinct gene expression profile, which is often accompanied by the spatial redistribution of heterochromatin into senescence-associated heterochromatic foci (SAHFs). Studying a key component of the nuclear lami...
Autores principales: | Sadaie, Mahito, Salama, Rafik, Carroll, Thomas, Tomimatsu, Kosuke, Chandra, Tamir, Young, Andrew R.J., Narita, Masako, Pérez-Mancera, Pedro A., Bennett, Dorothy C., Chong, Heung, Kimura, Hiroshi, Narita, Masashi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759696/ https://www.ncbi.nlm.nih.gov/pubmed/23964094 http://dx.doi.org/10.1101/gad.217281.113 |
Ejemplares similares
-
Cellular senescence and its effector programs
por: Salama, Rafik, et al.
Publicado: (2014) -
Chromatin remodeling, BRCA1, SAHF and cellular senescence
por: Tu, Zhigang, et al.
Publicado: (2013) -
Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition
por: Sadaie, Mahito, et al.
Publicado: (2015) -
Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53
por: Kirschner, Kristina, et al.
Publicado: (2015) -
Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks()()
por: Bilsland, Alan E., et al.
Publicado: (2015)