A new role for the cellular PABP repressor Paip2 as an innate restriction factor capable of limiting productive cytomegalovirus replication

The capacity of polyadenylate-binding protein PABPC1 (PABP1) to stimulate translation is regulated by its repressor, Paip2. Paradoxically, while PABP accumulation promotes human cytomegalovirus (HCMV) protein synthesis, we show that this is accompanied by an analogous increase in the abundance of Pa...

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Detalles Bibliográficos
Autores principales: McKinney, Caleb, Yu, Dong, Mohr, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759697/
https://www.ncbi.nlm.nih.gov/pubmed/23964095
http://dx.doi.org/10.1101/gad.221341.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759697/
https://www.ncbi.nlm.nih.gov/pubmed/23964095
http://dx.doi.org/10.1101/gad.221341.113

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