Enhancement of microhomology-mediated genomic rearrangements by transient loss of mouse Bloom syndrome helicase

Bloom syndrome, an autosomal recessive disorder of the BLM gene, confers predisposition to a broad spectrum of early-onset cancers in multiple tissue types. Loss of genomic integrity is a primary hallmark of such human malignancies, but many studies using disease-affected specimens are limited in th...

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Detalles Bibliográficos
Autores principales: Yamanishi, Ayako, Yusa, Kosuke, Horie, Kyoji, Tokunaga, Masahiro, Kusano, Kohji, Kokubu, Chikara, Takeda, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759722/
https://www.ncbi.nlm.nih.gov/pubmed/23908384
http://dx.doi.org/10.1101/gr.152744.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759722/
https://www.ncbi.nlm.nih.gov/pubmed/23908384
http://dx.doi.org/10.1101/gr.152744.112

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