The Y chromosome as a regulatory element shaping immune cell transcriptomes and susceptibility to autoimmune disease

Understanding the DNA elements that constitute and control the regulatory genome is critical for the appropriate therapeutic management of complex diseases. Here, using chromosome Y (ChrY) consomic mouse strains on the C57BL/6J (B6) background, we show that susceptibility to two diverse animal model...

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Detalles Bibliográficos
Autores principales: Case, Laure K., Wall, Emma H., Dragon, Julie A., Saligrama, Naresha, Krementsov, Dimitry N., Moussawi, Mohamad, Zachary, James F., Huber, Sally A., Blankenhorn, Elizabeth P., Teuscher, Cory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759723/
https://www.ncbi.nlm.nih.gov/pubmed/23800453
http://dx.doi.org/10.1101/gr.156703.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759723/
https://www.ncbi.nlm.nih.gov/pubmed/23800453
http://dx.doi.org/10.1101/gr.156703.113

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