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The Y chromosome as a regulatory element shaping immune cell transcriptomes and susceptibility to autoimmune disease
Understanding the DNA elements that constitute and control the regulatory genome is critical for the appropriate therapeutic management of complex diseases. Here, using chromosome Y (ChrY) consomic mouse strains on the C57BL/6J (B6) background, we show that susceptibility to two diverse animal model...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759723/ https://www.ncbi.nlm.nih.gov/pubmed/23800453 http://dx.doi.org/10.1101/gr.156703.113 |