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Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm

DNA methylation plays key roles in diverse biological processes such as X chromosome inactivation, transposable element repression, genomic imprinting, and tissue-specific gene expression. Sequencing-based DNA methylation profiling provides an unprecedented opportunity to map and compare complete DN...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Zhou, Yan, Lin, Nan, Lowdon, Rebecca F., Hong, Chibo, Nagarajan, Raman P., Cheng, Jeffrey B., Li, Daofeng, Stevens, Michael, Lee, Hyung Joo, Xing, Xiaoyun, Zhou, Jia, Sundaram, Vasavi, Elliott, GiNell, Gu, Junchen, Shi, Taoping, Gascard, Philippe, Sigaroudinia, Mahvash, Tlsty, Thea D., Kadlecek, Theresa, Weiss, Arthur, O’Geen, Henriette, Farnham, Peggy J., Maire, Cécile L., Ligon, Keith L., Madden, Pamela A.F., Tam, Angela, Moore, Richard, Hirst, Martin, Marra, Marco A., Zhang, Baoxue, Costello, Joseph F., Wang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759728/
https://www.ncbi.nlm.nih.gov/pubmed/23804400
http://dx.doi.org/10.1101/gr.156539.113