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Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome

Elucidating the pathophysiology and molecular attributes of common disorders as well as developing targeted and effective treatments hinges on the study of the relevant cell type and tissues. Pancreatic beta cells within the islets of Langerhans are centrally involved in the pathogenesis of both typ...

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Detalles Bibliográficos
Autores principales: Nica, Alexandra C., Ongen, Halit, Irminger, Jean-Claude, Bosco, Domenico, Berney, Thierry, Antonarakis, Stylianos E., Halban, Philippe A., Dermitzakis, Emmanouil T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759730/
https://www.ncbi.nlm.nih.gov/pubmed/23716500
http://dx.doi.org/10.1101/gr.150706.112