Acacetin and Chrysin, Two Polyphenolic Compounds, Alleviate Telomeric Position Effect in Human Cells

We took advantage of the ability of human telomeres to silence neighboring genes (telomere position effect or TPE) to design a high-throughput screening assay for drugs altering telomeres. We identified, for the first time, that two dietary flavones, acacetin and chrysin, are able to specifically al...

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Detalles Bibliográficos
Autores principales: Boussouar, Amina, Barette, Caroline, Nadon, Robert, Saint-Léger, Adelaïde, Broucqsault, Natacha, Ottaviani, Alexandre, Firozhoussen, Arva, Lu, Yiming, Lafanechère, Laurence, Gilson, Eric, Magdinier, Frédérique, Ye, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759739/
https://www.ncbi.nlm.nih.gov/pubmed/23962900
http://dx.doi.org/10.1038/mtna.2013.42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759739/
https://www.ncbi.nlm.nih.gov/pubmed/23962900
http://dx.doi.org/10.1038/mtna.2013.42

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