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A Practical Approach to Immunotherapy of Hepatocellular Carcinoma Using T Cells Redirected Against Hepatitis B Virus

Hepatocellular carcinoma (HCC) cells often have hepatitis B virus (HBV)-DNA integration and can be targeted by HBV-specific T cells. The use of viral vectors to introduce exogenous HBV-specific T-cell receptors (TCR) on T cells to redirect their specificity is complex and expensive to implement in c...

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Detalles Bibliográficos
Autores principales: Koh, Sarene, Shimasaki, Noriko, Suwanarusk, Rossarin, Ho, Zi Zong, Chia, Adeline, Banu, Nasirah, Wu Howland, Shanshan, Ong, Alice Soh Meoy, Gehring, Adam J, Stauss, Hans, Renia, Laurent, Sällberg, Matti, Campana, Dario, Bertoletti, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759740/
https://www.ncbi.nlm.nih.gov/pubmed/23941866
http://dx.doi.org/10.1038/mtna.2013.43